一、简历
董彪,公司唐敖庆领军教授,博士生导师,ylzz总站线路检测生物医学工程系主任,院学术委员会成员,教学委员会成员。近五年来,申请人依托公司集成光电子学国家重点实验室及生物医学工程系,聚焦于肿瘤、炎症等疾病诊疗中的若干挑战性难题,围绕 (1) 如何高效利用具有界面调控效应的纳米材料,并用于疾病标志物高灵敏度检测;(2) 如何通过新型光转化方式实现生物组织深部病灶的疾病诊疗和炎症调节;(3) 如何通过界面调控提升纳米敏感材料的电学性能,并用于炎症标志物检测等关键科学问题:提出了若干思路和解决方案,发展了多种基于纳米生物材料和技术的诊疗新策略。
研究方向为纳米生物材料及生物医学光子学,发表SCI收录论文180余篇,论文引用8000多次,H因子52。2017年以来,以通讯作者身份在Adv. Energy. Mater.、Adv. Funct. Mater.、Nano Today、Laser Photonics Review, Nano Energy、Small (2篇)、Biomaterials (3篇)、Theranostics (2篇)、Chem. Eng. J. (2篇)、ACS Appl. Mater. Inter. (3篇)、Adv. Healthcare Mater. (3篇)、Acta Biomaterialia、Journal of Materials Science & Technology (综述) 等著名期刊上发表相关成果,其中影响因子大于10的论文22篇,影响因子大于15的论文11篇,公司C刊论文7篇 (近5年);以第一发明人身份获得授权发明专利5项。
2016年获得了法中科学及应用基金会颁发的“吉尔卡恩奖,Gilles KAHN –Servier Prize 2016” (唯一获奖者);获得2019年吉林省自然科学一等奖 (排名第三);获得2018年公司优秀博士后一等奖以及公司首届课堂质量奖;2021年,被聘为公司唐敖庆领军教授 (领军B岗位)。
承担国家自然科学基金面上项目、基金委原创探索项目(1/2)、科技部大气专项子课题和吉林省自然科学基金等科研项目。应邀担任《发光学报》第一、二届青年编委,Sensors杂志编委,Journal of Nanomaterials杂志特约编辑,吉林省化学会医学与化学分会委员。
二、研究方向
1. 功能纳米材料的生物医学应用
2. 重大疾病标志物传感器
3. 稀土基光电材料及器件
三、承担科研项目
1. 基于磁性/上转换荧光探针及微流控芯片的循环肿瘤细胞富集和精准计数研究 (52272080),国家自然科学基金委-面上项目,54万。
2. 基于场增强效应的上转换荧光肿瘤标志物传感器 (61775080),国家自然
科学基金-面上项目63万。
3. 血管内捕获并同步杀死循环肿瘤细胞—阻遏肿瘤转移的新途径探索 (52050077), 100万元,国家自然科学基金委-首批原创探索项目
4. 室内典型化学污染物和颗粒物实时检测技术与器件研制 (2016YFC0207101)国家重点专项,119万,公司项目负责人
5. 基于稀土发光大唾液肿瘤标志物传感器 (20220402005GH),吉林省科技厅,国际合作项目,25万。
6. 半导体/稀土上转换纳米晶材料及其肿瘤诊疗一体化应用 (20170101170JC),吉林省自然科学基金,10万。
四、讲授课程
本科生课程:生物化学
研究生课程:生物医学光子学
五、代表性论文
(1) Fabrication, Optical Property, and White LED Application of Novel Lanthanide-Based Family Cs2NaLnX6 (X = Cl, Br, I) Perovskite Nanomaterials,Liheng Sun, Biao Dong, Jiao Sun, Yue Wang, Rui Sun, Songtao Hu, Bingshuai Zhou, Wen Xu, Xue Bai, Lin Xu, Donglei Zhou, Hongwei Song, Laser Photonics Rev, 2023,2300045
(2) Vitamin Natural Molecule Enabled Highly Efficient and Stable Planar N–P Homojunction Perovskite Solar Cells with Efficiency Exceeding 24.2%,Bin Liu, Yuqi Wang, Yanjie Wu, Yuhong Zhang, Jiekai Lyu, Zhongqi Liu, Shuhang Bian, Xue Bai, Lin Xu, Donglei Zhou, Biao Dong* and Hongwei Song* Adv. Energy Mater. 2023, 13, 2203352
(3) Gallium and gallium compounds: New insights into the ‘‘Trojan horse” strategy in medical applications, Wenyue Sun, Manlin Qi, Shi Cheng, Chunyan Li, Biao Dong*, Lin Wang*, Materials & Design 2023, 227, 111704
(4) Recent progress of nanostructure-based enrichment of circulating tumor cells and downstream analysis Lihua Guo, Chang Liu, Manlin Qi, Liang Cheng,* Lin Wang, Chunxia Li * and Biao Dong* Lab on a Chip 2023 DOI: 10.1039/d2lc00890d
(5) NIR responsive nitric oxide nanogenerator for enhanced biofilm eradication and inflammation immunotherapy against periodontal diseases,Manlin Qi, Xuan Ren, Wen Li, Yue Sun, Xiaolin Sun, Chunyan Li, Siyao Yu, Lin Xu, Yanmin Zhou, Shuyan Song, Biao Dong,* Lin Wang, Nano Today 2022, 43,101447
(6) Simultaneous Bottom-Up Double-layer Synergistic Optimization by Multifunctional Fused-Ring Acceptor with Electron-Deficient Core for Stable Planar Perovskite Solar Cells with Approaching 24% Efficiency, Bin Liu, Yuqi Wang, Yanjie Wu, Lin Xu, Biao Dong*, hongwei Song* Nano Energy, 2022, 99, 107368
(7) Upconversion luminescence based inverted microfluidic chip for in situ CTCs capture, monitor and killing,Jiekai Lyu, Hongwei Xu, Biao Dong*, Chunxia Li, Siyao Yu, Songtao Hu, Bingshuai Zhou, Lin Wang, Hongwei Song* Chemical Engineering Journal 2022, 448, 137761
(8) Dual-Responsive Nanocomposites for Synergistic Antibacterial Therapies Facilitating Bacteria-Infected Wound Healing. Shi Cheng, Manlin Qi, Wen Li, Wenyue Sun, Meiqi Li, Jingying Lin, Xue Bai, Yue Sun*, Biao Dong*, Lin Wang*. Advanced Healthcare Materials 2022, DOI: 10.1002/adhm.202202652.
(9) Antibacterial PDT nanoplatform capable of releasing therapeutic gas for synergistic and enhanced treatment against deep infections, Bingshuai Zhou, Xiaolin Sun, Biao Dong*, Siyao Yu, Liang Cheng, Songtao Hu, Wei Liu, Lin Xu, Xue Bai, Lin Wang, Hongwei Song, Theranostics, 2022; 12(6): 2580-2597
(10) Near-infrared-activated nanohybrid coating with black phosphorus/zinc oxide for efficient biofilm eradication against implant-associated infections, Jiao Fang, Yao Wan, Yue Sun, Xiaolin Sun, Manlin Qi, Shi Cheng, Chunyan Li, Yanmin Zhou, Lin Xu, Biao Dong*, Lin Wang* Chemical Engineering Journal 435 (2022) 134935
(11) Photonic Crystal Effects on Upconversion Enhancement of LiErF4:0.5%Tm3+@LiYF4 for Noncontact Cholesterol Detection Ling Zhang, Songtao Hu, Yang Lu, Bin Jiang, Xiaomin Liu, Xiaodan Li, Xu Zhao, Xu Yan, Chenguang Wang, Xiaoteng Jia, Fengmin Liu, Biao Dong,* and Geyu Lu*ACS Appl. Mater. Interfaces 2022, 14, 428−438
(12) Recent Progress in Fluorescent Probes For Metal Ion Detection (review), Luanjing Li, Jiahe Wang, Shihan Xu, Chunxia Li and Biao Dong* Frontiers in Chemistry, 2022, 10, 875241, Doi: 10.3389/fchem.2022.875241
(13) Oxygen Self-Su fficient Nanoplatform for Enhanced and Selective Antibacterial Photodynamic Therapy against Anaer obe-Induced Periodontal Disease, Xiaolin Sun; Jiao Sun; Yue Sun; Lin Xu; Yanmin Zhou; Lin Wang; Biao Dong*; Advanced Functional Materials, 2021, 2101040
(14) Quercetin-Loaded Ceria Nanocomposite Potentiate Du al-Directional Immunoregulation via Macrophage Polarization against Periodontal Inflammation, Wang, Yu; Li, Chunyan; Wan, Yao; Qi, Manlin; Chen, Qiuhan; Sun, Yue; Sun, Xiaolin; Fang, Jiao; Fu, Li; Xu, Lin; Biao Dong*; Wang, Lin ; Small, 2021, 17(41): 0-2101505
(15) Antibacterial Zeolite Imidazole Frameworks with Manganese Doping for Immunomodulation to Accelerate Infected Wound Healing, Yao Wan, Jiao Fang, Yu Wang, Jiao Sun, Yue Sun, Xiaolin Sun, Manlin Qi, Wen Li, Chunyan Li, Yanmin Zhou, Lin Xu,* Biao Dong,* and Lin Wang*, Adv. Healthcare Mater. 2021, 10, 2101515
(16) Double Stopband Bilayer Photonic Crystal Based Upconversion Fluorescence PSA SensorHu S.T., Xu H.W., Zhou B.S., Xu S.H., Shen B., Dong B.*, Mintova S., Song H.W., Sensors and Actuators B: Chemical, 2021, 326, 128816
(17) A versatile nanocomposite based on nanoceria for antibacterial enhancement and protection from aPDT-a ggravated inflammation via modulation of macrophage polarization, Yue Sun; Xiaolin Sun; Xue Li; Wen Li; Chunyan Li; Yanmin Zhou; Lin Wang; Biao Dong*; Biomaterials, 2020, 268: 20614
(18) Novel dental adhesive containing silver exchanged EMT zeolites against cariogenic biofilms to combat dental caries, Wen Lia, Manlin Qi, Xiaolin Sun, Lin Wang, Biao Dong* Microporous and Mesoporous Materials 2020, 299, 110113
(19) High fluorescence LaOBr/coumarin organic–inorganic composite nanomaterials for ultra-sensitive Fe3+ sensing, fluorescence imaging and water-based ink anti-counterfeiting applications,Liheng Sun, Jingshi Liu, Shihan Xu, Biao Dong, * Jiekai Lv, Songtao Hu, Bingshuai Zhou, Bo Shen, Yuqi Wang, Lin Xu, Wen Xu, Xue Bai and Hongwei Song J. Mater. Chem. C, 2020, 8, 13733
(20) Water-soluble coumarin oligomer based ultra-sensitive iron ion probe and applications Jingshi Liu, Yuan Guo, Biao Dong,* Jiao Sun, Jiekai Lyu, Liheng Sun, Songtao Hu,Lin Xu, Xue Bai, Wen Xu, Svetlana Mintova, Hongwei Song,* Sensors & Actuators: B. Chemical, 2020, 320, 128361
(21) Highly sensitive and selective acetone sensor based on three-dimensional ordered WO3/Au nanocomposite with enhanced performanceXinran Zhang, Biao Dong,* Wei Liu, Xiangyu Zhou, Min Liu, Xueke Sun, Jiekai Lv, Liangle Zhang, Wen Xu, Xue Bai, Lin Xu, Svetlana Mintova, Hongwei Song,* Sensors & Actuators: B. Chemical, 2020, 320, 128405
(22) Noninvasive temperature monitoring for dual-modal tumor therapy based on lanthanide-doped up-conversion nanocomposites, Xueke Sun, Jiao Sun, Biao Dong*, Xinran Zhang, Min Liu, Lin Xu, Xue Bai, Wen Xu, Hongwei Song, Biomaterials 2019, 201, 42–52
(23) Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe, Donglei Shi, Shuqiang Chen, Biao Dong (共同一作), Yanhui Zhang, Chunquan Sheng, Tony D. James and Yuan Guo, Chem. Sci., 2019, 10, 3715
(24) Surface treatments on titanium implants via nanostructured ceria for antibacterial and anti-inflammatory capabilities. Xue Li, Manlin Qi, Xiaolin Sun, Michael D. Weir, Franklin R. Tay, Thomas W. Oates, Biao Dong*, Yanmin Zhou, Lin Wang, Hockin H.K. Xu, Acta Biomaterialia 2019, 94, 627–643
(25) Novel nanotechnology and near-infrared photodynamic therapy to kill periodontitis-related biofilm pathogens and protect the periodontium,Manlin Qi, Xue Li, Xiaolin Sun, Chunyan Li, Franklin R. Tay,Michael D. Weir, Biao Dong*, Yanmin Zhoua, Lin Wang*, Hockin H.K. Xu Dental Materials 2019, 35, 1665-1681
(26) Ce6-C6-TPZ co-loaded albumin nanoparticles for synergistic combined PDT-chemotherapy of cancer, Xueke Sun, Jiao Sun, Jiekai Lv, Biao Dong,* Min Liu, Jingshi Liu, Liheng Sun, Guangji Zhang, Li Zhang, Gaosheng Huang, Wen Xu, Lin Xu,Xue Bai and Hongwei Song, J. Mater. Chem. B, 2019, 7, 5797
(27) Nanoparticles having amphiphilic silane containing Chlorin e6 with strong anti-biofilm activity against periodontitis-related pathogens, Xiaolin Sun, LinWang, Christopher D. Lynch, Xueke Sun, Xue Li, Manlin Qi, Cui Ma, Chunyan Li, Biao Dong*, Yanmin Zhou, Hockin H. K. Xu. Journal of Dentistry, 2019, 81, 70–84
(28) Xinran Zhang, Jiao Sun, Jingshi Liu, Hongwei Xu, Biao Dong*, Xueke Sun, Tianxiang Zhang, Shihan Xu, Lin Xu, Xue Bai, Shuang Zhang, Svetlana Mintova, Geyu Lu, Hongwei Song, Label-free electrochemical immunosensor based on conductive Ag contained EMT-style nano-zeolites and the application for α-fetoprotein detection, Sensors and Actuators B: Chemical, 2018, 255, 2919–2926
(29) Biao Dong, Richard Retoux, Vincent de Waele, Sandro G. Chiodo, Tzonka Mineva, Julien Cardin, Svetlana Mintova*, Sodalite cages of EMT zeolite confined neutral molecular-like silver clusters, Microporous and Mesoporous Materials 2017, 244, 74-82
(30) Xueke Sun, Biao Dong,* Hongwei Xu,; Shihan Xu, Xinran Zhang, Yanxia Lin, Lin Xu, Xue Bai, Shuang Zhang, Hongwei Song*, Amphiphilic silane modified multifunctional nanoparticles for magnetically targeted photodynamic therapy, ACS Applied Materials & Interfaces 2017, 9, 11451
(31) Hongwei Xu, Biao Dong,* Qiaoqin Xiao, Xueke Sun, Xinran Zhang, Jiekai Lyu, Yudan Yang, Lin Xu, Xue Bai, Shuang Zhang, and Hongwei Song, Three-Dimensional Inverse Opal Photonic Crystal Substrates toward Efficient Capture of Circulating Tumor Cells ACS Appl. Mater. Interfaces 2017, 9, 30510−30518
(32) Hongwei Xu, Biao Dong*, Shihan Xu, Sai Xu, Xueke Sun, Jiao Sun, Yudan Yang, Lin Xu, Xue Bai, Shuang Zhang, Ze Yin, Hongwei Song, High purity microfluidic sorting and in situ inactivation of circulating tumor cells based on multifunctional magnetic composites, Biomaterials 2017, 138, 69-79
(33) Lihang Zhang, Biao Dong*, Lin Xu, Xinran Zhang, Jianjun Chen, Xueke Sun, Hongwei Xu, Tianxiang Zhang, Xue Bai, Shuang Zhang, Hongwei Song, Three-dimensional ordered ZnO–Fe3O4 inverse opal gas sensortoward trace concentration acetone detection,Sensors and Actuators B 2017, 252, 367–374
(34) Tianxiang Zhang, Hongwei Xu, He Wang, Jinyang Zhu, Yue Zhai, Xue Bai, Biao Dong* and Hongwei Song, Green fluorescent organic nanoparticles based on carbon dots and self-polymerized dopamine for cell imaging, RSC Adv., 2017, 7, 28987
(35) Yanxia Lin, Hongwei Xu, Biao Dong,* Xueke Sun, Chunhe Li, Jianing Li, Lin Xu, Xue Bai and Hongwei Song, Amphiphilic silane modified multifunctional nanoparticles for ratiometric oxygen sensing RSC Adv., 2017, 7, 34118
六、专利
(1) 董彪; 吕杰凯; 李春霞; 孙娇; 宋宏伟; 王林; 白雪; 徐琳 ; 捕获和/或计数细胞的微流控芯片及其制备方法和应用, 2022-3-3, 中国, 202011133693.3
(2) 董彪; 胡松涛; 宋宏伟; 孙娇; 李春霞; 王林; 徐琳; 白雪 ; 一种提高蛋白石光子晶体薄膜水/机械稳定性的方法, 2021-3-5, 中国, 202110244854.4 (专利 )
(3) 董彪; 刘静诗; 孙娇; 洪德成; 徐琳; 白雪; 宋宏伟 ; 一种用于检测Fe3+的有机荧光传感探针及制备 方法、使用方法和应用, 2020-1-17, 中国, ZL201810487433.2
(4) 董彪; 许红威; 徐诗函; 宋宏伟; 白雪; 徐琳; 孙雪珂 ; 用于循环肿瘤细胞捕获的纳米结构微流控芯片及其制备方法, 2018-3-22, 中国, 201610247371.9
(5) 董彪; 宋宏伟; 王宇; 白雪; 徐琳 ; 稀土上转换纳米晶/银双功能复合纳米材料及制备方法及在癌症检测与治疗中的应用, 2013-4-17, 中国, CN201010274976.X
七、学术奖励情况
(1) 2016吉尔卡恩奖“Gilles KAHN –Servier Prize 2016”唯一获奖者,法中科学及应用基金会 La Fondation Franco-Chinoise pour la Science et ses Applications (FFCSA)
(2) 2019年度-吉林省自然科学一等奖“稀土纳米晶的光电性能调控与应用研”, 排名第三,宋宏伟; 董斌; 董彪; 白雪; 徐琳; 徐文; 张振翼
(3) 2018年,公司优秀博士后一等奖
(4) 2018年,公司课堂教学质量奖
(5) Au@mSiO2复合纳米材料的合成及生物应用探索 “Frist prize for the best poster presentation”2013.09 第五届介孔微孔材料国际会议,保加利亚,5th International Symposium Advanced Micro- & Mesoporous Materials”
(6) 2010年,吉林省科技进步一等奖,“强紫外上转换发光材料及其特性的研究”,秦伟平,宋宏伟,秦冠仕,王宇,赵丹,张继森,董彪,白雪
八、毕业生去向
高校、科研院所,国内电子、生物技术公司等。
九、联系方式
所在单位:公司,ylzz总站线路检测,生物医学工程系
邮箱:dongb@jlu.edu.cn
手机号码:13504329842(微信)